Chemical Structure : Dronedarone
CAS No.: 141626-36-0
Catalog No.: PC-46030Not For Human Use, Lab Use Only.
Dronedarone (SR33589) is a multichannel blocker agent that has antiarrhythmic activity, reduces the late sustained K(+) current, I(K) (or Isus) with EC50 of 0.85 uM in postmyocardial infarcted (PMI) rats.
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	Dronedarone (SR33589) is a multichannel blocker agent that has antiarrhythmic activity, reduces the late sustained K(+) current, I(K) (or Isus) with EC50 of 0.85 uM in postmyocardial infarcted (PMI) rats.
	Dronedarone reduces significantly the incidence of ventricular fibrillation (VF) in rats.
	Dronedarone mainly used for treatment of cardiac arrhythmias.
| M.Wt | 556.7565 | |
| Formula | C31H44N2O5S | |
| Appearance | Solid | |
| Storage | 
                            
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| Solubility | 
                             10 mM in DMSO  | 
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| Chemical Name/SMILES | 
                             Methanesulfonamide, N-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-5-benzofuranyl]-  | 
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1. Aimond F, et al. J Pharmacol Exp Ther. 2000 Jan;292(1):415-24.
2. Sun W, et al. Circulation. 1999 Nov 30;100(22):2276-81.
3. Manakshe G, et al. Indian Heart J. 2012 Mar-Apr;64(2):182-6.

                
                
                
                
                
                
                
                
            
            
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