You are here:Home-Chemical Inhibitors & Agonists-Membrane Transporter/Ion Channel-Potassium Channel-Dronedarone hydrochloride
Dronedarone hydrochloride

Chemical Structure : Dronedarone hydrochloride

CAS No.: 141625-93-6

Dronedarone hydrochloride (SR-33589 hydrochloride)

Catalog No.: PC-45962Not For Human Use, Lab Use Only.

A multichannel blocker agent that has antiarrhythmic activity.

Packing Price Stock Quantity
50 mg $124 In stock
250 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A multichannel blocker agent that has antiarrhythmic activity; reduces the late sustained K(+) current, I(K) (or Isus) with EC50 of 0.85 uM in postmyocardial infarcted (PMI) rats; reduces significantly the incidence of ventricular fibrillation (VF) in rats; mainly used for treatment of cardiac arrhythmias.

Heart Arrhythmia

Approved

Physicochemical Properties

M.Wt 593.2174
Formula C31H45ClN2O5S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Methanesulfonamide, N-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-5-benzofuranyl]-, hydrochloride (1:1)

References

1. Aimond F, et al. J Pharmacol Exp Ther. 2000 Jan;292(1):415-24.

2. Sun W, et al. Circulation. 1999 Nov 30;100(22):2276-81.

3. Manakshe G, et al. Indian Heart J. 2012 Mar-Apr;64(2):182-6.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: