Drp1 inhibitor P110

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Chemical Structure : Drp1 inhibitor P110

Catalog No.: PC-24289Not For Human Use, Lab Use Only.

Drp1 inhibitor P110 (Compound P110) is a selective Drp1 peptide inhibitor with neuroprotective properties, inhibits the activation of Drp1, prevent MPTP-induced Drp1 mitochondrial translocation.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Drp1 inhibitor P110 (Compound P110) is a selective Drp1 peptide inhibitor with neuroprotective properties, inhibits the activation of Drp1, prevent MPTP-induced Drp1 mitochondrial translocation.
P110 alleviates MPTP-induced dopaminergic neuron loss, dopaminergic nerve terminal damage, and behavioral deficits.
P110 reduces mitochondrial damage and organ injury in animal models of Huntington's disease, cerebral ischemic injury, and myocardial infarction.

Physicochemical Properties

M.Wt	2411.78
Formula	C100H179N45O25
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Gly-Asp-Leu-Leu-Pro-Arg-Gly-Ser-NH2

References

1. Emily Filichia, et al. Sci Rep. 2016 Sep 13:6:32656.

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