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Drpitor1

Chemical Structure : Drpitor1

CAS No.: 73540-73-5

Drpitor1

Catalog No.: PC-26857Not For Human Use, Lab Use Only.

Drpitor1 is a selective, potent dynamin-related protein 1 (Drp1) inhibitor with IC50 of 0.09 uM for mitochondrial fragmentation, inhibits the GTPase activity of Drp1 without inhibiting the GTPase of dynamin 1.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Drpitor1 is a selective, potent dynamin-related protein 1 (Drp1) inhibitor with IC50 of 0.09 uM for mitochondrial fragmentation, inhibits the GTPase activity of Drp1 without inhibiting the GTPase of dynamin 1.

Physicochemical Properties

M.Wt 292.29
Formula C17H12N2O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

6-(methoxymethyl)-5H-pyrido[4,3-b]carbazole-5,11(6H)-dione

References

1. Danchen Wu, et al. FASEB J. 2020 Jan;34(1):1447-1464.

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