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Dulaglutide

Chemical Structure : Dulaglutide

CAS No.: 923950-08-7

Dulaglutide (LY2189265, LY-2189265)

Catalog No.: PC-27453Not For Human Use, Lab Use Only.

Dulaglutide (LY2189265) is a long-acting glucagon-like peptide-1 analog and GLP-1 receptor agonist, shows full receptor activity in vitro and elicits insulinotropic activity in islets similar to native peptide, increases glucose tolerance.

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Biological Activity

Dulaglutide (LY2189265) is a long-acting glucagon-like peptide-1 analog and GLP-1 receptor agonist, shows full receptor activity in vitro and elicits insulinotropic activity in islets similar to native peptide, increases glucose tolerance.

Physicochemical Properties

M.Wt 62561 (Glycosylation, Dominant form)
Formula
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

DPP-IV-protected GLP-1(7–37) analogue fused to a modified immunoglobulin G (IgG4) Fc fragment

References

1. Skrivanek Z, et al. J Diabetes Sci Technol. 2012 Nov 1;6(6):1305-18.

2. Barrington P, et al. Diabetes Obes Metab. 2011 May;13(5):434-8.

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