Duloxetine | SNRI | Probechem Biochemicals

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Chemical Structure : Duloxetine

CAS No.: 116539-59-4

Duloxetine ((S)-Duloxetine, LY248686, LY-248686)

Catalog No.: PC-26223Not For Human Use, Lab Use Only.

Duloxetine (LY248686) is a potent serotonin-norepinephrine reuptake inhibitor (SNRI) with Ki of 4.6 nM, also inhibitsvoltage-dependent K+ channels (Kv channels) with IC50 of 4.95 uM for arterial Kv currents.

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25 mg	$78	In stock
100 mg	$128	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Physicochemical Properties

M.Wt	297.42
Formula	C18H19NOS
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-N-Methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propan-1-amine

References

1. De Berardis, D. et al. Int J Immunopathol Pharmacol, 2010. 23(2): p. 417-22.

2. Jeong J, et al. Eur J Pharmacol. 2025 Oct 15;1005:178110.

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Duloxetine ((S)-Duloxetine, LY248686, LY-248686)

Biological Activity

Physicochemical Properties

References

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