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Chemical Structure : Dutacatib
Catalog No.: PC-20203Not For Human Use, Lab Use Only.
Dutacatib (AFG495) is potent, selective and non-covalent cathepsin K inhibitor with IC50 of 3-6 nM (human CatK), shows excellent selectivity profile versus human cathepsins L and S.
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Dutacatib (AFG495) is potent, selective and non-covalent cathepsin K inhibitor with IC50 of 3-6 nM (human CatK), shows excellent selectivity profile versus human cathepsins L and S.
| M.Wt | 421.55 | |
| Formula | C23H31N7O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Eva Altmann, et al. J Med Chem. 2002 Jun 6;45(12):2352-4.
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