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Dynein inhibitor 20

Chemical Structure : Dynein inhibitor 20

CAS No.: 2663697-25-2

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Dynein inhibitor 20

Catalog No.: PC-73232Not For Human Use, Lab Use Only.

Dynein inhibitor 20 is a small moelcule inhibitor of S. cerevisiae dynein by engaging the regulatory ATPase sites in AAA3 and AAA4 domains.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Dynein inhibitor 20 is a small moelcule inhibitor of S. cerevisiae dynein by engaging the regulatory ATPase sites in AAA3 and AAA4 domains.
    Dynein inhibitor 20 does not interact with dynein's main catalytic site in the AAA1 domain.

    Physicochemical Properties

    M.Wt 481.734
    Formula C22H14BrClN4O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    6-(3-bromophenoxy)-2-(1-(4-chlorophenyl)cyclopropyl)-7-hydroxypyrazolo[1,5-a]pyrimidine-3-carbonitrile

    References

    1. Cristina C Santarossa, et al. Cell Chem Biol. 2021 Oct 21;28(10):1460-1473.e15.

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