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Chemical Structure : E-2012
CAS No.: 870843-42-8
Catalog No.: PC-42071Not For Human Use, Lab Use Only.
E-2012 (E2012) is a potent, second-generation γ-secretase modulator that decreases Aβ(1-39), Aβ(1-40) and A(1-42), and increases Aβ(1-37).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $118 | In stock | |
| 10 mg | $178 | In stock | |
| 25 mg | $298 | In stock | |
| 50 mg | $488 | In stock | |
| 100 mg | Get quote |
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E-2012 (E2012) is a potent, second-generation γ-secretase modulator that decreases Aβ(1-39), Aβ(1-40) and A(1-42), and increases Aβ(1-37).
| M.Wt | 419.4912 | |
| Formula | C25H26FN3O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-Piperidinone, 1-[(1S)-1-(4-fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]methylene]-, (3E)- |
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1. Portelius E, et al. J Alzheimers Dis. 2010;21(3):1005-12.
2. Borgegard T, et al. J Biol Chem. 2012 Apr 6;287(15):11810-9.
3. Borghys H, et al. J Alzheimers Dis. 2012;28(4):809-22.
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