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EAI001

Chemical Structure : EAI001

CAS No.: 892772-75-7

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EAI001 (EAI-001, EAI 001)

Catalog No.: PC-21850Not For Human Use, Lab Use Only.

EAI001 is a potent, mutant-selectiveepidermal growth factor receptor (EGFR) allosteric inhibitor with IC50 value of 24 nM for EGFRL858R/T790M.

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10 mg $128 In stock
25 mg $198 In stock
50 mg $298 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

EAI001 is a potent, mutant-selectiveepidermal growth factor receptor (EGFR) allosteric inhibitor with IC50 value of 24 nM for EGFRL858R/T790M.

Physicochemical Properties

M.Wt 349.41
Formula C19H15N3O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(3-oxo-1H-isoindol-2-yl)-2-phenyl-N-(1,3-thiazol-2-yl)acetamide

References

1. Maity S, et al. Pharmacol Rep. 2020 Aug;72(4):799-813.

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