EDD3 |CAS:25279-15-6 Probechem Biochemicals

You are here:Home-Chemical Inhibitors & Agonists-Wnt/Notch/Hedgehog-Notch-EDD3

Chemical Structure : EDD3

CAS No.: 25279-15-6

EDD3 (EDD 3)

Catalog No.: PC-60556Not For Human Use, Lab Use Only.

A novel Notch inhibitor that reduces protein expression of NOTCH1, NICD and HES1 in HEK293 cells and downregulates Notch target genes.

Packing	Price	Stock
2 mg	$558	In stock
5 mg	$898	In stock
10 mg		Get quote
25 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

EDD3 is a novel Notch inhibitor that reduces protein expression of NOTCH1, NICD and HES1 in HEK293 cells and downregulates Notch target genes.
EDD3 inhibits proliferation and induces G0/G1 cell cycle arrest of ORL-150 cells through inducing p27KIP1.

Physicochemical Properties

M.Wt	474.726
Formula	C30H50O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(8R,10R,12R,14R,17S)-12-hydroxy-17-((2S,5R)-5-(2-hydroxypropan-2-yl)-2-methyltetrahydrofuran-2-yl)-4,4,8,10,14-pentamethylhexadecahydro-3H-cyclopenta[a]phenanthren-3-one

References

1. Velaithan V, et al. Invest New Drugs. 2017 Apr;35(2):166-179.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com

EDD3 (EDD 3)

Biological Activity

Physicochemical Properties

References

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

Get Quote

* Indicates a Required FieldYour information is safe with us.