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EGFR-targeting peptide GE11

Chemical Structure : EGFR-targeting peptide GE11

CAS No.: 875142-25-9

EGFR-targeting peptide GE11

Catalog No.: PC-24922Not For Human Use, Lab Use Only.

EGFR-targeting peptide GE11 is an epidermal growth factor receptor (EGFR)-specific ligand for active targeting of EGFR-overexpressing cancer cells, Conjugation of GE11 peptides to liposomal constructs enhances anti-tumor efficacies and specificities in laryngeal cancer cells.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

EGFR-targeting peptide GE11 is an epidermal growth factor receptor (EGFR)-specific ligand for active targeting of EGFR-overexpressing cancer cells, Conjugation of GE11 peptides to liposomal constructs enhances anti-tumor efficacies and specificities in laryngeal cancer cells.

Physicochemical Properties

M.Wt 1540.70
Formula C75H97N17O19
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

L-Isoleucine, L-tyrosyl-L-histidyl-L-tryptophyl-L-tyrosylglycyl-L-tyrosyl-L-threonyl-L-prolyl-L-glutaminyl-L-asparaginyl-L-valyl-

References

1. Klutz K, et al. Mol Ther. 2011 Apr;19(4):676-85.

2. Schäfer A, et al. Hum Gene Ther. 2011 Dec;22(12):1463-73.

3. Master AM, et al. Nanomedicine. 2012 Jul;8(5):655-64.

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