EP2 receptor antagonist CJ-18

Chemical Structure : EP2 receptor antagonist CJ-18

Catalog No.: PC-28504Not For Human Use, Lab Use Only.

EP2 receptor antagonist CJ-18 is a highly potent, brain-penetrant EP2 receptor antagonist with Kb value of 5.0 nM, reduces ischaemic brain injury by modulating neuroinflammation.

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Biological Activity

EP2 receptor antagonist CJ-18 is a highly potent, brain-penetrant EP2 receptor antagonist with Kb value of 5.0 nM, reduces ischaemic brain injury by modulating neuroinflammation.

Physicochemical Properties

M.Wt	385.47
Formula	C23H23N5O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-(2-methyl-1H-indol-3-yl)ethyl)-6-((6-methylpyridin-2-yl)amino)nicotinamide

References

1. Jin Z, et al. Br J Pharmacol. 2026 Oct 13. doi: 10.1111/bph.70709.

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