Catalog No.: PC-22065Not For Human Use, Lab Use Only.
ESB1609 is a potent, selective, next-generation S1P5 receptor agonist with EC50 of 70 nM at the human S1P5 receptor, has >700-fold selectivity over human S1P1, S1P2, S1P3, and S1P4 receptors (EC50>5 uM).
ESB1609 is a potent, selective, next-generation S1P5 receptor agonist with EC50 of 70 nM at the human S1P5 receptor, has >700-fold selectivity over human S1P1, S1P2, S1P3, and S1P4 receptors (EC50>5 uM).
ESB1609 is classified as a nonsubstrate of P-glycoprotein, the breast cancer resistance protein, and the human organic anion transporting polypeptides 1B1 and 1B3.
ESB1609 can be a potential therapeutic for a variety of neurodegenerative and lysosomal storage diseases.
