Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
EN | CN

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-Membrane Transporter/Ion Channel-iGluR-EU1622-240
EU1622-240

Chemical Structure : EU1622-240

CAS No.: 3057728-22-7

Add to Favorites

EU1622-240

Catalog No.: PC-23269Not For Human Use, Lab Use Only.

EU1622-240 is a positive allosteric modulator of NMDA receptors (NMDARs), enhances current response to saturating agonist (doubling response amplitude at 0.2-0.5 µM).

Packing Price Stock Quantity
50 mg Get quote
100 mg Get quote
250 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC)

Biological Activity

EU1622-240 is a positive allosteric modulator of NMDA receptors (NMDARs), enhances current response to saturating agonist (doubling response amplitude at 0.2-0.5 µM).
EU1622-240-bound NMDARs channels activated by a single agonist (glutamate or glycine) open to a unique conductance level with different pore properties and Mg2+ sensitivity, in contrast to channels arising from activation of NMDARs with both co-agonists bound.

Physicochemical Properties

M.Wt 478.31
Formula C20H14BrF2N3O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5-(3-bromo-4-fluorophenyl)-6-ethynyl-3-(2-(3-fluoro-3-methylazetidin-1-yl)-2-oxoethyl)thieno[2,3-d]pyrimidin-4(3H)-one

References

1. Elijah Z Ullman, et al. Mol Pharmacol. 2024 Oct 23:MOLPHARM-AR-2024-001019.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: