EU93-31 | GluN2B antagonist | Probechem Biochemicals

Chemical Structure : EU93-31

EU93-31 (Compound 93-31)

Catalog No.: PC-26194Not For Human Use, Lab Use Only.

EU93-31 is a potent, pH-sensitive GluN2B-selective antagonist of NMDA receptor with IC50 of 0.19 uM (GluN1/GluN2B, pH=6.9) and 1.8 uM (GluN1/GluN2B, pH=7.6).

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Biological Activity

EU93-31 is a potent, pH-sensitive GluN2B-selective antagonist of NMDA receptor with IC50 of 0.19 uM (GluN1/GluN2B, pH=6.9) and 1.8 uM (GluN1/GluN2B, pH=7.6).

Physicochemical Properties

M.Wt	489.45
Formula	C22H30Cl2N2O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-N-(4-(3-(butyl(3,4-dichlorophenethyl)amino)-2-hydroxypropoxy)phenyl)methanesulfonamide

References

1. Yuan H, et al. Neuron. 2015 Mar 18;85(6):1305-1318.

2. Harris LD, et al. ACS Chem Neurosci. 2023 Mar 1;14(5):917-935.

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EU93-31 (Compound 93-31)

Biological Activity

Physicochemical Properties

References

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