EVT-101 | GluN2B antagonist | Probechem Biochemicals

Chemical Structure : EVT-101

Catalog No.: PC-26196Not For Human Use, Lab Use Only.

EVT-101 is a highly potent, selective and orally active GluN2B antagonist with IC50 of 12 nM for GluN1/GluN2B.

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Biological Activity

EVT-101 is a highly potent, selective and orally active GluN2B antagonist with IC50 of 12 nM for GluN1/GluN2B.

M.Wt	318.30
Formula	C16H13F3N4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	5-(3-(difluoromethyl)-4-fluorophenyl)-3-((2-methyl-1H-imidazol-1-yl)methyl)pyridazine

1. Fernandes A, et al. Eur J Pharmacol. 2015 Nov 5;766:1-8.

2. Stroebel D, et al. Mol Pharmacol. 2016 May;89(5):541-51.