Chemical Structure : Edicotinib
CAS No.:
1142363-52-7
Edicotinib
(JNJ-40346527, JNJ 40346527, PRV 6527, JNJ-527)
Catalog No. : PC-61373Not For Human Use, Lab Use Only.
Edicotinib (JNJ-40346527, PRV 6527) is a potent, selective, orally bioavailable CSF-1R inhibitor with IC50 of 3.2 nM.
Packing Price Stock Quantity 5 mg $128 In stock 0 1 2 3 4 5 10 mg $198 In stock 0 1 2 3 4 5 25 mg $328 In stock 0 1 2 3 4 5 50 mg $528 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6137301
Biological Activity
Edicotinib (JNJ-40346527, PRV 6527) is a potent, selective, orally bioavailable CSF-1R inhibitor with IC50 of 3.2 nM.
Physicochemical Properties
M.Wt
461.61
Formula
C27H35N5O2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
4-cyano-N-[2-(4,4-dimethylcyclohex-1-en-1-yl)-6-(2,2,6,6-tetramethyloxan-4-yl)pyridin-3-yl]-1H-imidazole-2-carboxamide
References
1. von Tresckow B, et al. Clin Cancer Res.
2. Genovese MC, et al. J Rheumatol.
3. Pass HI, et al. Oncotarget.
4. Kumar V, et al. Cancer Cell.
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