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Edivoxetine hydrochloride

Chemical Structure : Edivoxetine hydrochloride

CAS No.: 1194374-05-4

Edivoxetine hydrochloride (LY2216684 hydrochloride)

Catalog No.: PC-61998Not For Human Use, Lab Use Only.

Edivoxetine (LY2216684) is a novel potent, selective norepinephrine reuptake inhibitor (NERI) being evaluated as adjunctive treatment for major depressive disorder (MDD)..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Edivoxetine (LY2216684) is a novel potent, selective norepinephrine reuptake inhibitor (NERI) being evaluated as adjunctive treatment for major depressive disorder (MDD).

Depression

Discontinued

Physicochemical Properties

M.Wt 375.865
Formula C18H27ClFNO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(R)-2-(5-fluoro-2-methoxyphenyl)-1-((S)-morpholin-2-yl)-1-(tetrahydro-2H-pyran-4-yl)ethan-1-olhydrochloride

References

1. Kielbasa W, et al. Eur J Clin Pharmacol. 2013 Dec;69(12):2011-9.

2. Kielbasa W, et al. J Clin Pharmacol. 2015 Dec;55(12):1422-31.

3. Kielbasa W, et al. J Child Adolesc Psychopharmacol. 2012 Aug;22(4):269-76.

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