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Chemical Structure : Elesclomol
CAS No.: 488832-69-5
Catalog No.: PC-42855Not For Human Use, Lab Use Only.
Elesclomol (STA-4783) is a small-molecule oxidative stress inducer, exerts selective cytotoxicity by increasing intracellular concentrations of reactive oxygen species (ROS) and induces cell death via mitochondrial apoptosisin cancer cells.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $95 | In stock | |
| 25 mg | $295 | In stock | |
| 100 mg | $725 | In stock | |
| 500 mg | Get quote |
Bulk size, bulk discount!
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Elesclomol (STA-4783) is a small-molecule oxidative stress inducer, exerts selective cytotoxicity by increasing intracellular concentrations of reactive oxygen species (ROS) and induces cell death via mitochondrial apoptosisin cancer cells; selectively kills cisplatin-resistant tumor cells through increased ROS, markedly enhances the therapeutic index of paclitaxel against human tumor xenograft models.
Ovarian Cancer
Phase 2 Clinical
| M.Wt | 400.5177 | |
| Formula | C19H20N4O2S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 22 mg/mL |
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| Chemical Name/SMILES |
Propanedioic acid, 1,3-bis[2-methyl-2-(phenylthioxomethyl)hydrazide] |
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1. Berkenblit A, et al. Clin Cancer Res. 2007 Jan 15;13(2 Pt 1):584-90.
2. Kirshner JR, et al. Mol Cancer Ther. 2008 Aug;7(8):2319-27.
3. Wangpaichitr M, et al. Cancers (Basel). 2009;1(1):23-38.
4. Kluza J, et al. Cancer Res. 2012 Oct 1;72(19):5035-47.
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