Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Eliprodil
CAS No.: 119431-25-3
Catalog No.: PC-43279Not For Human Use, Lab Use Only.
Eliprodil (SL-820715) is a non-competitive NR2B-NMDA receptor (GluN2B) antagonist with IC50 of 1 uM, less potent for NR2A- and NR2C-containing receptors (IC50>100 uM).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $98 | In stock | |
| 25 mg | $158 | In stock | |
| 50 mg | $258 | In stock | |
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Eliprodil (SL-820715) is a non-competitive NR2B-NMDA receptor (GluN2B) antagonist with IC50 of 1 uM, less potent for NR2A- and NR2C-containing receptors (IC50>100 uM).
Eliprodil inhibits [3H]norepinephrine release from cortical and hippocampal slices but enhances the basal efflux of endogenous and tritiated dopamine from striatal slices.
Eliprodil also blocks the uptake of [3H]dopamine into striatal synaptosomes with IC50 of 1.5 uM.
Eliprodil reduces the volume of infarction in models of focal cerebral ischemia.
| M.Wt | 347.8541 | |
| Formula | C20H23ClFNO | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
1-Piperidineethanol, α-(4-chlorophenyl)-4-[(4-fluorophenyl)methyl]- |
|
1. Woodward JJ, et al. Eur J Pharmacol. 1992 Jan 21;210(3):265-70.
2. Carter CJ, et al. J Pharmacol Exp Ther. 1990 May;253(2):475-82.
3. Carter C, et al. Eur J Pharmacol. 1989 May 30;164(3):611-2.
4. Bath CP, et al. Eur J Pharmacol. 1996 Mar 28;299(1-3):103-12.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
