Catalog No.: PC-45289Not For Human Use, Lab Use Only.
Embelin (Embelic acid, Emberine, NSC-91874) is a cell-permeable benzoquinone compound that exhibits antitumor properties, specifically antagonizes XIAP-mediated inhibition of caspase-9 activation by directly targeting the Smac and caspase-9 binding domain BIR3 (IC50=4.1 uM).
Embelin (Embelic acid, Emberine, NSC-91874) is a cell-permeable benzoquinone compound that exhibits antitumor properties, specifically antagonizes XIAP-mediated inhibition of caspase-9 activation by directly targeting the Smac and caspase-9 binding domain BIR3 (IC50=4.1 uM).
Embelin has anti-inflammatory activities in both acute and chronic irritant contact dermatitis in vivo.
Embelin also inhibits plasminogen activator inhibitor-1 (PAI-1) with IC50 of 1.62 uM.
