Chemical Structure : Empagliflozin
CAS No.: 864070-44-0
Catalog No.: PC-22576Not For Human Use, Lab Use Only.
Empagliflozin (BI-10773) is a potent, selective sodium glucose cotransporter-2 (SGLT-2) inhibitor with IC50 of 3.1 nM (hSGLT-2), has a high degree of selectivity over SGLT-1, 4, 5 and 6, has potential for the oral treatment of type 2 diabetes mellitus (T2DM).
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100 mg | $98 | In stock | |
500 mg | $168 | In stock | |
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Empagliflozin (BI-10773) is a potent, selective sodium glucose cotransporter-2 (SGLT-2) inhibitor with IC50 of 3.1 nM (hSGLT-2). has a high degree of selectivity over SGLT-1, 4, 5 and 6, has potential for the oral treatment of type 2 diabetes mellitus (T2DM).
M.Wt | 450.91 | |
Formula | C23H27ClO7 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-(((S)-tetrahydrofuran-3-yl)oxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol |
1. Aires I, et al. Curr Opin Investig Drugs. 2010 Oct;11(10):1182-90.
2. Grempler R, et al. Diabetes Obes Metab. 2012 Jan;14(1):83-90.
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