Emzeltrectinib

Chemical Structure : Emzeltrectinib

Catalog No.: PC-20031Not For Human Use, Lab Use Only.

Emzeltrectinib is a potent, selective neurotrophic factor tyrosine kinase receptor TrkB inhibitor, shows potential for treatment of Trk kinase-mediated tumor.

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Biological Activity

Emzeltrectinib is a potent, selective neurotrophic factor tyrosine kinase receptor TrkB inhibitor, shows potential for treatment of Trk kinase-mediated tumor.

Physicochemical Properties

M.Wt	376.34
Formula	C17H15F3N6O
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-amino-5-((2R,4S)-2-(2,5-difluorophenyl)-4-fluoropyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

References

1. Patent WO2018077246 A1

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Emzeltrectinib

Biological Activity

Physicochemical Properties

References

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