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Enalaprilat

Chemical Structure : Enalaprilat

CAS No.: 76420-72-9

Enalaprilat (MK-422 anhydrous)

Catalog No.: PC-27011Not For Human Use, Lab Use Only.

Enalaprilat (MK-422 anhydrous) is the active metabolite of Enalapril, is a potent, competitive and long-acting angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.94 nM.

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Biological Activity

Enalaprilat (MK-422 anhydrous) is the active metabolite of Enalapril, is a potent, competitive and long-acting angiotensin-converting enzyme (ACE) inhibitor with IC50 of 1.94 nM.

Physicochemical Properties

M.Wt 348.40
Formula C18H24N2O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-1-((S)-2-(((S)-1-Carboxy-3-phenylpropyl)amino)propanoyl)pyrrolidine-2-carboxylic acid

References

1. Eickels M, et, al. Br J Pharmacol. 2000 Dec;131(8):1592-6.

2. Ceconi C, et, al. Eur J Pharmacol. 2007 Dec 22;577(1-3):1-6.

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