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Endomorphin-1

Chemical Structure : Endomorphin-1

CAS No.: 189388-22-5

Endomorphin-1 (EM1, EM-1, Endomorphin 1)

Catalog No.: PC-26572Not For Human Use, Lab Use Only.

Endomorphin-1 (EM-1, Endomorphin 1) a high affinity, highly selective agonist mu-opioid receptor (muOR, μOR) agonist with Ki of 1.11 nM, displays reasonable affinities for kappa3 binding sites, has antinociceptive properties.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Endomorphin-1 (EM-1, Endomorphin 1) a high affinity, highly selective agonist mu-opioid receptor (muOR, μOR) agonist with Ki of 1.11 nM, displays reasonable affinities for kappa3 binding sites, has antinociceptive properties.

Physicochemical Properties

M.Wt 610.72
Formula C34H38N6O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Tyr-Pro-Trp-Phe-NH(2)

References

1. Harrison C, et al. Br J Pharmacol. 1999 Sep;128(2):472-8.

2. Zhang WP, et al. Mol Med Rep. 2016 Oct;14(4):3992-8.

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