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Chemical Structure : Enmetazobactam
CAS No.: 1001404-83-6
Catalog No.: PC-61972Not For Human Use, Lab Use Only.
Enmetazobactam (AAI-101) is a novel extended-spectrum β-lactamase inhibitor with activity against many β-lactamases, including some class A and class D carbapenemases.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $128 | In stock | |
| 25 mg | $218 | In stock | |
| 50 mg | $348 | In stock | |
| 100 mg | Get quote |
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Enmetazobactam (AAI-101) is a novel extended-spectrum β-lactamase inhibitor with activity against many β-lactamases, including some class A and class D carbapenemases.
Enmetazobactam (AAI-101) is currently in clinical development as a combination with cefepime.
Enmetazobactam (AAI-101) reduces the MIC50 of cefepime against a collection of 223 cefepime-nonsusceptible isolates of the family Enterobacteriaceae from >64 mg/L to 0.125 mg/L.
| M.Wt | 314.32 | |
| Formula | C11H14N4O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(2S,3S,5R)-3-methyl-3-((1-methyl-1H-1,2,3-triazol-3-ium-3-yl)methyl)-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 4,4-dioxide |
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1. Crandon JL, et al. Antimicrob Agents Chemother. 2015 May;59(5):2688-94.
2. Crandon JL, et al. Pathogens. 2015 Aug 18;4(3):620-5.
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