Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Antibiotics and Antivirals-Bacterial-Enoxacin hydrate
Enoxacin hydrate

Chemical Structure : Enoxacin hydrate

CAS No.: 84294-96-2

Enoxacin hydrate (AT-2266 hydrate, CI-919 hydrate)

Catalog No.: PC-23989Not For Human Use, Lab Use Only.

Enoxacin hydrate (Enoxacin sesquihydrate) is a fluoroquinolone antibiotic, interferes with DNA replication and inhibits bacterial DNA gyrase (IC50=126 µg/ml) and topoisomerase IV (IC50=26.5 µg/ml).

Packing Price Stock Quantity
100 mg $38 In stock
500 mg $68 In stock
1 g $98 In stock
5 g Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Enoxacin hydrate (Enoxacin sesquihydrate) is a fluoroquinolone antibiotic, interferes with DNA replication and inhibits bacterial DNA gyrase (IC50=126 µg/ml) and topoisomerase IV (IC50=26.5 µg/ml).
Enoxacin hydrate is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs.
Enoxacin shows potent activities against gram-positive and -negative bacteria.
Enoxacin hydrate is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing.

Physicochemical Properties

M.Wt 347.34
Formula C15H17FN4O3.3/2H2O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid

References

1. Ge Shan, et al. Nat Biotechnol. 2008 Aug;26(8):933-40.

2. Sonia Melo, et al. Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4394-9.

3. M Takei, et al. Antimicrob Agents Chemother. 2001 Dec;45(12):3544-7.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: