Chemical Structure : Enoxacin hydrate
CAS No.: 84294-96-2
Catalog No.: PC-23989Not For Human Use, Lab Use Only.
Enoxacin hydrate (Enoxacin sesquihydrate) is a fluoroquinolone antibiotic, interferes with DNA replication and inhibits bacterial DNA gyrase (IC50=126 µg/ml) and topoisomerase IV (IC50=26.5 µg/ml).
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Enoxacin hydrate (Enoxacin sesquihydrate) is a fluoroquinolone antibiotic, interferes with DNA replication and inhibits bacterial DNA gyrase (IC50=126 µg/ml) and topoisomerase IV (IC50=26.5 µg/ml).
Enoxacin hydrate is a miRNA processing activator and enhances siRNA-mediated mRNA degradation and promotes the biogenesis of endogenous miRNAs.
Enoxacin shows potent activities against gram-positive and -negative bacteria.
Enoxacin hydrate is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2 (TRBP)-mediated microRNA processing.
M.Wt | 347.34 | |
Formula | C15H17FN4O3.3/2H2O | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid |
1. Ge Shan, et al. Nat Biotechnol. 2008 Aug;26(8):933-40.
2. Sonia Melo, et al. Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4394-9.
3. M Takei, et al. Antimicrob Agents Chemother. 2001 Dec;45(12):3544-7.
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