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Eperezolid

Chemical Structure : Eperezolid

CAS No.: 165800-04-4

Eperezolid (PNU-100592, PNU100592, U-100592)

Catalog No.: PC-42560Not For Human Use, Lab Use Only.

Eperezolid (PNU-100592) is an oxazolidinone antibiotic that possesses potent antimicrobial activity in vitro and in vivo, binds specifically to the 50S ribosomal subunit of Escherichia coli.

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Biological Activity

Eperezolid (PNU-100592) is an oxazolidinone antibiotic that possesses potent antimicrobial activity in vitro and in vivo, binds specifically to the 50S ribosomal subunit of Escherichia coli.
Eperezolid exhibits potent in vitro inhibitory activity, regardless of methicillin susceptibility for staphylococci(MIC90= 1-4 mg/ml).

Physicochemical Properties

M.Wt 394.3974
Formula C18H23FN4O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 44 mg/mL

Chemical Name/SMILES

Acetamide, N-[[(5S)-3-[3-fluoro-4-[4-(2-hydroxyacetyl)-1-piperazinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl]-

References

1. Ford CW, et al. Antimicrob Agents Chemother. 1996 Jun;40(6):1508-13.

2. Zurenko GE, et al. Antimicrob Agents Chemother. 1996 Apr;40(4):839-45.

3. Ford CW, et al. Antimicrob Agents Chemother. 1996 Jun;40(6):1508-13.

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