Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.

You are here:Home-Chemical Inhibitors & Agonists-Metabolic Enzyme/Protease-Carboxypeptidase-EpoY
EpoY

Chemical Structure : EpoY

CAS No.: 245660-13-3

EpoY (SD-142)

Catalog No.: PC-28343Not For Human Use, Lab Use Only.

EpoY (SD-142) is an irreversible inhibitor of brain's primary tubulin tyrosine carboxypeptidase (TCP) with IC50 of 500 nM, a complex formed by vasohibin-1 (VASH1) and the small vasohibin binding protein (SVBP), effectively decreases levels of detyrosinated alpha-tubulin, which is crucial for microtubule dynamics and neuronal differentiation.

Packing Price Stock Quantity
5 mg $218 In stock
10 mg $358 In stock
25 mg $558 In stock
50 mg Get quote
100 mg Get quote

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

EpoY (SD-142) is an irreversible inhibitor of brain's primary tubulin tyrosine carboxypeptidase (TCP) with IC50 of 500 nM, a complex formed by vasohibin-1 (VASH1) and the small vasohibin binding protein (SVBP), effectively decreases levels of detyrosinated alpha-tubulin, which is crucial for microtubule dynamics and neuronal differentiation.

Physicochemical Properties

M.Wt 323.30
Formula C15H17NO7
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

((2S,3S)-3-(Ethoxycarbonyl)oxirane-2-carbonyl)-L-tyrosine

References

1. Aillaud C, et al. Science. 2017 Dec 15;358(6369):1448-1453.

2. Eaton DM, et al. Sci Transl Med. 2024 Jul 17;16(756):eadm8842.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: