Epothilone D | Microtubule stabilizer | Probechem Biochemicals

Chemical Structure : Epothilone D

CAS No.: 189453-10-9

Epothilone D (Desoxyepothilone B, dEpoB)

Catalog No.: PC-23848Not For Human Use, Lab Use Only.

Epothilone D (KOS 862) is a potent microtubule stabilizer, inhibits CCRF-CEM/VBL1000 cells (2,048-fold resistance to vinblastine) with IC50 of 2.9 nM.

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5 mg	$158	In stock
10 mg	$248	In stock
25 mg	$428	In stock
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Biological Activity

Epothilone D (KOS 862) is a potent microtubule stabilizer, inhibits CCRF-CEM/VBL1000 cells (2,048-fold resistance to vinblastine) with IC50 of 2.9 nM.

Physicochemical Properties

M.Wt	491.69
Formula	C27H41NO5S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(4S,7R,8S,9S,13Z,16S)-4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-[(E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-1-oxacyclohexadec-13-ene-2,6-dione

References

1. Chou TC, et al. Proc Natl Acad Sci U S A. 2001 Jul 3;98(14):8113-8.

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Epothilone D (Desoxyepothilone B, dEpoB)

Biological Activity

Physicochemical Properties

References

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