Erasin | STAT3 inhibitor | Probechem Biochemicals

Chemical Structure : Erasin

CAS No.: 2256056-21-8

Erasin (STAT3 inhibitor Erasin)

Catalog No.: PC-61033Not For Human Use, Lab Use Only.

Erasin is a potent, selective STAT3 inhibitor with IC50 of 9.7 uM, inhibits tyrosine phosphorylation of STAT3 with selectivity over STAT5 and STAT1 in cell-based assays.

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5 mg	$78	In stock
10 mg	$118	In stock
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Biological Activity

Erasin is a potent, selective STAT3 inhibitor with IC50 of 9.7 uM, inhibits tyrosine phosphorylation of STAT3 with selectivity over STAT5 and STAT1 in cell-based assays.
Erasin induces apoptosis in Erlotinib-resistant lung cancer cells.

Physicochemical Properties

M.Wt	349.39
Formula	C20H19N3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-N'-((6-(tert-butyl)-4-oxo-4H-chromen-3-yl)methylene)nicotinohydrazide

References

1. Lis C, et al. Sci Rep. 2017 Dec 12;7(1):17390.

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Erasin (STAT3 inhibitor Erasin)

Biological Activity

Physicochemical Properties

References

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