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Erastin

Chemical Structure : Erastin

CAS No.: 571203-78-6

Erastin

Catalog No.: PC-22423Not For Human Use, Lab Use Only.

Erastin is a specific ferroptosis-inducing compound, shows RAS-selective lethality, also targetsvoltage-dependent anion channel 3 (VDAC3).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Erastin is a specific ferroptosis-inducing compound, shows RAS-selective lethality, also targetsvoltage-dependent anion channel 3 (VDAC3).

Physicochemical Properties

M.Wt 547.05
Formula C30H31ClN4O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(1-(4-(2-(4-Chlorophenoxy)acetyl)piperazin-1-yl)ethyl)-3-(2-ethoxyphenyl)quinazolin-4(3H)-one

References

1. Dolma S, et al. Cancer Cell. 2003 Mar;3(3):285-96.

2. Sun X, et al. Oncogene. 2015 Nov 5;34(45):5617-25.

3. Yang WS, et al. Chem Biol. 2008 Mar;15(3):234-45.

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