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ErbB4 inhibitor Compound IIa

Chemical Structure : ErbB4 inhibitor Compound IIa

CAS No.: 2766149-95-3

ErbB4 inhibitor Compound IIa

Catalog No.: PC-72062Not For Human Use, Lab Use Only.

ErbB4 inhibitor Compound IIa is a first-in-class, potent, selective ErbB4 (HER4) inhibitor with IC50 of 17.7 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    ErbB4 inhibitor Compound IIa is a first-in-class, potent, selective ErbB4 (HER4) inhibitor with IC50 of 17.7 nM.

    Physicochemical Properties

    M.Wt 384.457
    Formula C22H16N4OS
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    6-(3-(benzyloxy)phenyl)-5-(pyrimidin-4-yl)imidazo[2,1-b]thiazole

    References

    1. Seyed-Omar Zaraei, et al. Eur J Med Chem. 2021 Nov 15;224:113674.

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