Chemical Structure : Ercalcidiol
CAS No.:
21343-40-8
Ercalcidiol
(1,25-Dihydroxyvitamin D2;1,25-Dihydroxycalciferol)
Catalog No. : PC-45807Not For Human Use, Lab Use Only.
The active circulating metabolite of vitamin D2 that binds to nuclear receptor VDR.
Packing Price Stock Quantity 5 mg $328.8 In stock 0 1 2 3 4 5 10 mg $493.6 In stock 0 1 2 3 4 5 25 mg $1080 In stock 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4580701
Biological Activity
The active circulating metabolite of vitamin D2 that binds to nuclear receptor VDR; activates VDR to interact with retinoid X receptor (RXR) and forms the VDR/RXR/cofactor complex, which binds to Vitamin D response elements in the promoter region of target genes to regulate gene transcription.
Physicochemical Properties
M.Wt
412.6478
Formula
C28H44O2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
Cyclohexanol, 4-methylene-3-[(2E)-2-[(1R,3aS,7aR)-octahydro-1-[(1R,2E,4S)-5-hydroxy-1,4,5-trimethyl-2-hexenyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1S,3Z)-
References
1. Nakane M, et al. J Steroid Biochem Mol Biol. 2006 Jan;98(1):72-7.
2. Hollis BW. Nutr Rev. 2007 Aug;65(8 Pt 2):S87-90.
3. Hollis BW, et al. J Steroid Biochem Mol Biol. 2007 Mar;103(3-5):473-6.
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