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Chemical Structure : Erianin
CAS No.: 95041-90-0
Catalog No.: PC-21593Not For Human Use, Lab Use Only.
Erianin is a small molecule inhibitor of CRAF and MEK1/2 kinases, inhibits constitutive activation of MAPK signaling pathway.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $128 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | $288 | In stock | |
| 100 mg | Get quote |
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Erianin is a small molecule inhibitor of CRAF and MEK1/2 kinases, inhibits constitutive activation of MAPK signaling pathway.
Erianin inhibits constitutive activation of MAPK signaling pathway through suppressing CRAF and MEK1/2 but not BRAF kinase activity.
Erianin inhibits proliferation in BRAF V600E or RAS mutant cell lines.
Erianin suppresses either BRAF V600E or RAS mutant cell growth in CDX model.
| M.Wt | 318.37 | |
| Formula | C18H22O5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-Methoxy-5-(3,4,5-trimethoxyphenethyl)phenol |
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1. Wang P, et al. Signal Transduct Target Ther. 2023;8:96.
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