Erianin

Chemical Structure : Erianin

CAS No.: 95041-90-0

Catalog No.: PC-21593Not For Human Use, Lab Use Only.

Erianin is a small molecule inhibitor of CRAF and MEK1/2 kinases, inhibits constitutive activation of MAPK signaling pathway.

Packing	Price	Stock
10 mg	$128	In stock
25 mg	$198	In stock
50 mg	$288	In stock
100 mg		Get quote

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Biological Activity

Erianin is a small molecule inhibitor of CRAF and MEK1/2 kinases, inhibits constitutive activation of MAPK signaling pathway.
Erianin inhibits constitutive activation of MAPK signaling pathway through suppressing CRAF and MEK1/2 but not BRAF kinase activity.
Erianin inhibits proliferation in BRAF V600E or RAS mutant cell lines.
Erianin suppresses either BRAF V600E or RAS mutant cell growth in CDX model.

Physicochemical Properties

M.Wt	318.37
Formula	C18H22O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Methoxy-5-(3,4,5-trimethoxyphenethyl)phenol

References

1. Wang P, et al. Signal Transduct Target Ther. 2023;8:96.

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Erianin

Biological Activity

Physicochemical Properties

References

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