Eribaxaban (PD-0348292) is a potent, selective and orally efficacious factor Xa (FXa) inhibitor with IC50 of 0.32 nM.
Eribaxaban (PD-0348292) displays >1,000-fold selectivity over a series of related serine proteases (thrombin, activated protein C, plasmin, tissue plasminogen activator and trypsin).
Eribaxaban (PD-0348292) potently inhibits thrombosis and shows potential for s for the treatment and prevention of thrombotic disorders.
