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Chemical Structure : Etamicastat hydrochloride
CAS No.: 677773-32-9
Catalog No.: PC-22597Not For Human Use, Lab Use Only.
Etamicastat hydrochloride (BIA 5-453 hydrochloride) is a potent, peripherally selective and reversible dopamine-β-hydroxylase (DβH) inhibitor with IC50 of 107 nM, reduces the biosynthesis of norepinephrine (noradrenaline).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $348 | In stock | |
| 10 mg | $548 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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Etamicastat hydrochloride (BIA 5-453 hydrochloride) is a potent, peripherally selective and reversible dopamine-β-hydroxylase (DβH) inhibitor with IC50 of 107 nM, reduces the biosynthesis of norepinephrine (noradrenaline).
| M.Wt | 347.81 | |
| Formula | C14H16ClF2N3OS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(R)-5-(2-aminoethyl)-1-(6,8-difluorochroman-3-yl)-1,3-dihydro-2H-imidazole-2-thione hydrochloride |
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1. Beliaev A, et al. J Med Chem. 2006 Feb 9;49(3):1191-7.
2. Loureiro AI, et al. Eur J Pharmacol. 2014 Oct 5;740:285-94.
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