Etoposide | Topo II inhibitor, CD44 inhibitor

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Chemical Structure : Etoposide

CAS No.: 33419-42-0

Etoposide (VP-16, VP-16-213)

Catalog No.: PC-27536Not For Human Use, Lab Use Only.

Etoposide (VP-16-213) is a topoisomerase II inhibitor that disrupts DNA replication and transcription, induces cell cycle arrest, apoptosis and autophagy, also inhibits Hyaluronic acid (HA)-CD44 interaction.

Packing	Price	Stock
50 mg	$28	In stock
250 mg	$58	In stock
500 mg	$88	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Physicochemical Properties

M.Wt	588.56
Formula	C29H32O13
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(5R,5aR,8aR,9S)-9-(((4aR,6R,7R,8R,8aS)-7,8-Dihydroxy-2-methylhexahydropyrano[3,2-d][1,3]dioxin-6-yl)oxy)-5-(4-hydroxy-3,5-dimethoxyphenyl)-5,5a,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(8H)-one

References

1. Fuchs, J., et al. Cancer. 1998. 83(11): p. 2400-7.

2. Chayah M, et al. Bioorg Chem. 2025 Mar;156:108212.

3. Hande KR, et al. Oncologist. 1996;1(4):234-239.

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Etoposide (VP-16, VP-16-213)

Biological Activity

Physicochemical Properties

References

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