Etravirine |CAS:269055-15-4 Probechem Biochemicals

Chemical Structure : Etravirine

CAS No.: 269055-15-4

Catalog No.: PC-46011Not For Human Use, Lab Use Only.

Etravirine (R-165335;TMC-125) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) for treatment of HIV-1 infection.

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Biological Activity

Etravirine (R-165335;TMC-125) is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) for treatment of HIV-1 infection.

M.Wt	435.2767
Formula	C20H15BrN6O
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzonitrile, 4-[[6-amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl-

1. Das K, et al. J Med Chem, 2004, 47(10), 2550-2560.

2. Andries K, et al. Antimicrob Agents Chemother. 2004 Dec;48(12):4680-6.

3. Sankatsing SU, et al. AIDS. 2003 Dec 5;17(18):2623-7.