Evixapodlin (GS-4224) | PD-1/PD-L1 inhibitor

Chemical Structure : Evixapodlin

CAS No.: 2374856-75-2

Evixapodlin (GS-4224, GS4224)

Catalog No.: PC-38391Not For Human Use, Lab Use Only.

Evixapodlin (GS-4224) is a highly potent, small molecule human PD-1/PD-L1 protein-protein interaction inhibitor with IC50 of 0.213 nM, exhibits potential anticancer and antiviral activities.

Packing	Price	Stock
5 mg	$198	In stock
10 mg	$298	In stock
25 mg	$488	In stock
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Biological Activity

Evixapodlin (GS-4224) is a highly potent, small molecule human PD-1/PD-L1 protein-protein interaction inhibitor with IC50 of 0.213 nM, exhibits potential anticancer and antiviral activities.

Physicochemical Properties

M.Wt	691.61
Formula	C34H36Cl2N8O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(5S,5'S)-5,5'-(((((2,2'-dichloro-[1,1'-biphenyl]-3,3'-diyl)bis(3-methoxypyrazine-5,2-diyl))bis(methylene))bis(azanediyl))bis(methylene))bis(pyrrolidin-2-one)

References

1. Patent WO2019160882A1 (compound number 139).

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Evixapodlin (GS-4224, GS4224)

Biological Activity

Physicochemical Properties

References

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