Catalog No.: PC-28466Not For Human Use, Lab Use Only.
Exatecan mesylate (DX-8951f) is a potent DNA topoisomerase I (Topo I) inhibitor with IC50 of 2.2 μM (0.975 μg/mL), exerts its cytotoxic effect by trapping the TOP1-DNA cleavage complex (TOP1cc), is a cytotoxic payload for ADCs.
Exatecan mesylate (DX-8951f) is a potent DNA topoisomerase I (Topo I) inhibitor with IC50 of 2.2 μM (0.975 μg/mL), exerts its cytotoxic effect by trapping the TOP1-DNA cleavage complex (TOP1cc), is a cytotoxic payload for ADCs.
