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Exendin-P5

Chemical Structure : Exendin-P5

CAS No.:

Exendin-P5 (ExP5)

Catalog No.: PC-25477Not For Human Use, Lab Use Only.

Exendin-P5 (ExP5) is a potent, selective, G protein-biased peptide agonist of GLP-1 receptor (GLP-1R), with diminished coupling to β-arrestins.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Exendin-P5 (ExP5) is a potent, selective, G protein-biased peptide agonist of GLP-1 receptor (GLP-1R), with diminished coupling to β-arrestins.

Physicochemical Properties

M.Wt 4209.71
Formula C185H291N49O61S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Sequence: Glu-Leu-Val-Asp-Asn-Ala-Val-Gly-Gly-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ala

References

1. Deganutti G, et al. Nat Commun. 2022 Jan 10;13(1):92.

2. Yi-Lynn Liang, et al. Nature. 2018 Mar 1;555(7694):121-125.

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