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Ezutromid

Chemical Structure : Ezutromid

CAS No.: 945531-77-1

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Ezutromid (SMT-C1100;VOX-C1100;BMN-195)

Catalog No.: PC-45388Not For Human Use, Lab Use Only.

The first orally bioavailable small molecule utrophin upregulator.

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10 mg $120 In stock
50 mg $416 In stock
100 mg $704 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

The first orally bioavailable small molecule utrophin upregulator; demonstrates significant disease modifying effects in DMD models; reduces a number of the pathological effects of dystrophin deficiency, results in reduced pathology, better muscle physiology leading to an increase in overall strength, and an ability to resist fatigue after forced exercise.

Other Indication

Phase 2 Clinical

Physicochemical Properties

M.Wt 337.3923
Formula C19H15NO3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: 10 mg/mL
Chemical Name/SMILES

Benzoxazole, 5-(ethylsulfonyl)-2-(2-naphthalenyl)-

References

1. Tinsley JM, et al. PLoS One. 2011 May 6;6(5):e19189.

2. Tinsley J, et al. J Clin Pharmacol. 2015 Jun;55(6):698-707.

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