FAK inhibitor E10

Chemical Structure : FAK inhibitor E10

Catalog No.: PC-25159Not For Human Use, Lab Use Only.

FAK inhibitor E10 is a potent and highly selective FAK inhibitor with IC50 of 2.55 nM.

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Biological Activity

FAK inhibitor E10 is a potent and highly selective FAK inhibitor with IC50 of 2.55 nM.

M.Wt	512.57
Formula	C28H28N6O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-Methoxy-4-((4-((3-oxo-2,3-dihydro-1H-inden-4-yl)oxy)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)-N-(piperidin-4-yl)benzamide

1. Wei W, et al. J Med Chem. 2025 Jul 31. doi: 10.1021/acs.jmedchem.5c00921.

2. Wei W, et al. Eur J Med Chem. 2022;228:113978.