Chemical Structure : FCCP
CAS No.: 370-86-5
Catalog No.: PC-22179Not For Human Use, Lab Use Only.
FCCP is a small molecule mitochondrial uncoupler of oxidative phosphorylation (OXPHOS), induces activation of PINK1 leading to Parkin Ser65 phosphorylation, proton ionophore and mitophagy inducer.
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FCCP is a small molecule mitochondrial uncoupler of oxidative phosphorylation (OXPHOS), induces activation of PINK1 leading to Parkin Ser65 phosphorylation, proton ionophore and mitophagy inducer.
M.Wt | 254.17 | |
Formula | C10H5F3N4O | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Carbonyl cyanide 4-(trifluoromethoxy) phenyl-hydrazone |
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2. Tanpradit N, et al. J Assist Reprod Genet. 2016 Dec;33(12):1621-1631.
3. Gautier CA, et al. Mol Neurodegener. 2012 May 25;7:22.
4. Gao F, et al. Aging Cell. 2020 Sep;19(9):e13211.
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