Chemical Structure : FD028
Catalog No.: PC-73248Not For Human Use, Lab Use Only.
FD028 is a small-molecule HIV-1 inactivator by conjugating FD016 (gp120-CD4 binding inhibitor) with FD017 (HIV-1 fusion inhibitor), inactivates cell-free virions (IC50=0.7 uM) of by targeting both HIV-1 gp120 and gp41.
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FD028 is a small-molecule HIV-1 inactivator by conjugating FD016 (gp120-CD4 binding inhibitor) with FD017 (HIV-1 fusion inhibitor), inactivates cell-free virions (IC50=0.7 uM) of by targeting both HIV-1 gp120 and gp41.
FD028 is not significantly toxic and has broad-spectrum HIV-1 inhibitory and inactivation activity, including T20-resistant viruses and T2635-resistant viruses.
M.Wt | 881.812 | |
Formula | C42H39Cl2FN4O8S2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Jing Pu, et al. Front Pharmacol. 2021 Jan 25;11:613361. doi: 10.3389/fphar.2020.613361.
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