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Chemical Structure : FF-10501-01
Catalog No.: PC-61690Not For Human Use, Lab Use Only.
FF-10501-01 is a potent, selective and orally available IMPDH inhibitor.
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FF-10501-01 is a potent, selective and orally available IMPDH inhibitor.
FF-10501-01 effectively induces AML cell death and reduces AML peripheral blood cell proliferation (mean IC50=14.6 uM) by targeting guanine nucleotide biosynthesis regardless of HMA resistance status.
| M.Wt | 562.45 | |
| Formula | C4H5N3O2.3/4H2O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Yang H, et al. Leuk Res. 2017 Aug;59:85-92.
2. Murase M, et al. Pharmacol Res Perspect. 2016 Jan 28;4(1):e00206.
3. Ichii M, et al. Leuk Lymphoma. 2017 Jul 21:1-12.
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