Chemical Structure : FFN-206 dihydrochloride
CAS No.: 1883548-88-6
Catalog No.: PC-62373Not For Human Use, Lab Use Only.
FFN-206 is an excellent VMAT2 (vesicular monoamine transporter 2) substrate capable of detecting VMAT2 activity in intact cells using fluorescence microscopy, with subcellular localization to VMAT2-expressing acidic compartments without apparent labeling of other organelles.
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FFN-206 dihydrochloride is an excellent VMAT2 (vesicular monoamine transporter 2) substrate capable of detecting VMAT2 activity in intact cells using fluorescence microscopy, with subcellular localization to VMAT2-expressing acidic compartments without apparent labeling of other organelles.
The apparent Km of FFN206 at VMAT2 was found to be 1.16±0.10 uM, similar to that of dopamine.
FFN-206 is an useful tool for optical examination of VMAT2 function in cell culture.
M.Wt | 291.172 | |
Formula | C12H16Cl2N2O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
4-(2-Aminoethyl)-7-(methylamino)-2H-1-benzopyran-2-one dihydrochloride |
1. Hu G, et al. ACS Chem Biol. 2013 Sep 20;8(9):1947-54.
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