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FG-944

Chemical Structure : FG-944

CAS No.: 2413574-64-6

FG-944 (FG944)

Catalog No.: PC-72375Not For Human Use, Lab Use Only.

FG944 (FG-944) is a potent selective LpxC inhibitor with MIC50 of 0.5 ug/mL against K.pneumoniae, synergizes with rifampin in carbapenem resistant K. pneumoniae and E. coli.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

FG944 (FG-944) is a potent selective LpxC inhibitor with MIC50 of 0.5 ug/mL against K.pneumoniae, synergizes with rifampin in carbapenem resistant K. pneumoniae and E. coli.

Physicochemical Properties

M.Wt 509.60
Formula C30H31N5O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-Azetidinecarbonitrile, 1-[(2S)-3-(1,6-dihydro-5-hydroxy-6-oxo-4-pyrimidinyl)-2-[4-[2-[4-(4-morpholinylmethyl)phenyl]ethynyl]phenyl]propyl]-

References

1. Min T, et al. LPXC INHIBITOR, FORMULATIONS, AND USES THEREOF:, US20210315902A1

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